Paper 3

CDISC Genius AI: PoC on how to interact with CDISC Library API using Natural language

September 23, 2025: 10:00 AM - 10:30 AM

Intermediate and Advanced Coding Skills (IACS), Breakout Room #9

Authors	Abstract
Saikrishnareddy Yengannagari	Is it possible to interact with CDISC Library API using Natural Language in plain English. Answer is Yes, we can. This paper presents a web application that allows users to query SDTM variable information using natural language by utilizing AI-driven natural language processing (NLP). Users can ask questions like "Tell me about AESER" or "What is VSTEST?" through the app. and to obtain accurate data, the AI extracts the name of the relevant variable. In addition, the application enables the generation of an entire SDTM specification from the SDTMIG version that is supplied, such as SDTMIG v3.4. After that, it automatically creates a sheet of specification data in Excel that can be downloaded from the CDISC API. This solution demonstrates the effectiveness of combining AI with API data retrieval to simplify clinical data specification and access, providing researchers and developers with a streamlined, automated procedure.

Saikrishnareddy Yengannagari

Is it possible to interact with CDISC Library API using Natural Language in plain English. Answer is Yes, we can. This paper presents a web application that allows users to query SDTM variable information using natural language by utilizing AI-driven natural language processing (NLP). Users can ask questions like "Tell me about AESER" or "What is VSTEST?" through the app. and to obtain accurate data, the AI extracts the name of the relevant variable. In addition, the application enables the generation of an entire SDTM specification from the SDTMIG version that is supplied, such as SDTMIG v3.4. After that, it automatically creates a sheet of specification data in Excel that can be downloaded from the CDISC API. This solution demonstrates the effectiveness of combining AI with API data retrieval to simplify clinical data specification and access, providing researchers and developers with a streamlined, automated procedure.